Predictors of Microvascular Reperfusion After Myocardial Infarction

Abstract Purpose of Review In acute ST-segment elevation myocardial infarction (STEMI), successful restoration blood flow in the infarct-related coronary artery may not secure effective reperfusion. The mortality and morbidity associated with MI remain significant. Microvascular obstruction (MVO) represents failed microvascular MVO is under-recognized, independently adverse cardiac prognosis an unmet therapeutic need. Recent Findings Multiple factors including clinical presentation, patient characteristics, biochemical markers, imaging parameters are after MI. Summary Impaired reperfusion common following percutaneous intervention (PCI). New knowledge about disease mechanisms underpins precision medicine individualized risk assessment, investigation, stratified therapy. To date, there no evidence-based therapies to prevent or treat post-MI. Identifying novel therapy for next frontier.